Living in Spain · Pets

Leishmaniasis in Dogs in Spain: Prevention & Treatment

Canine leishmaniasis (Leishmania infantum) is one of the most serious health threats facing dogs in Spain. Spread by the bite of tiny sandflies, it is endemic across much of the Mediterranean and the Iberian Peninsula. This guide explains how it spreads, where and when the risk is highest, the symptoms to watch for, how it is diagnosed, the reality of treatment and lifelong management, how to protect your dog — and why ongoing conditions like this are exactly what pet insurance is designed to help with.

Based on veterinary & parasitology guidance (ESCCAP, CAPC, LeishVet)Sandfly season, symptoms & prevention explainedThe honest truth about treatment and costEnglish-speaking pet-insurance advisers
Get Pet Insurance →
⚠ Leishmaniasis at a glance
CauseSandfly bite (Leishmania infantum)
Risk seasonWarm months (approx. Apr–Oct)
Curable?Managed, not always cured
PreventionEssential
How to protect your dog →

⚠ If your dog shows skin sores, hair loss around the eyes, weight loss or lethargy, see a vet — early diagnosis matters.

The disease

What is canine leishmaniasis?

Canine leishmaniasis (also spelled leishmaniosis) is a chronic, potentially life-threatening parasitic disease caused by a single-celled parasite called Leishmania infantum. It is one of the most important vector-borne diseases affecting dogs in southern Europe, and Spain — along with the rest of the Iberian Peninsula — is considered an endemic region, meaning the parasite is well established and present year after year.

The disease has been part of life for dogs in the Mediterranean basin for a very long time, but for many expats moving to Spain with a pet, it comes as a genuine shock. In the UK, Ireland, northern Europe and much of North America, leishmaniasis is rare or essentially absent, so owners simply have not had to think about it. In Spain it is a mainstream veterinary concern that responsible owners plan for from the moment they arrive.

What makes leishmaniasis different from a one-off emergency — such as a snake bite or contact with a processionary caterpillar — is that it is a slow, insidious, long-term condition. A dog can be infected for months or even more than a year before obvious signs appear, and once the disease takes hold it typically requires ongoing veterinary care for the rest of the dog’s life. That is a crucial point for both your dog’s welfare and your finances, and it runs right through this guide.

A quick note on terminology. You will see the disease written as both “leishmaniasis” and “leishmaniosis”. They refer to the same thing — “leishmaniosis” is the form generally preferred in European veterinary literature, while “leishmaniasis” is the more common everyday spelling. We use them interchangeably here.

Leishmaniasis is also a zoonotic disease, meaning the parasite can, in principle, affect people as well as dogs. However, people do not catch it directly from their dog — both dogs and humans are infected the same way, through a sandfly bite. Human cases in Spain are relatively uncommon and tend to affect people with weakened immune systems. The information in this guide is about protecting your dog; for any concern about human health, speak to your doctor.

Transmission

How leishmaniasis spreads: the sandfly

Leishmaniasis is spread almost entirely by the bite of the phlebotomine sandfly — a tiny, delicate insect distantly related to mosquitoes and midges. Sandflies are only two to three millimetres long, roughly a third of the size of a mosquito, and they are silent fliers, so most owners never notice them. When an infected sandfly bites a dog, it injects the Leishmania parasite into the skin, where it can go on to spread through the body.

Understanding the sandfly’s behaviour is the single most useful thing you can do, because prevention is built entirely around avoiding its bite. A few key facts stand out:

  • They are most active at dusk, through the night and at dawn. Sandflies are nocturnal insects that emerge from around sunset and remain active into the first hours of darkness and again around first light. The middle of a hot, bright day is generally low risk.
  • They prefer warm, still, humid conditions. Activity peaks in the warmer months. In much of Spain the sandfly season runs broadly from spring into autumn, with the greatest activity through the summer.
  • They breed in organic debris. Sandflies develop in dark, damp, sheltered spots — leaf litter, cracks in walls, animal shelters, compost, drains and rubble — rather than in open water like mosquitoes.
  • They are weak fliers. They tend to stay low and near the ground and do not travel far, which is why measures right around where your dog sleeps make a real difference.
Is leishmaniasis contagious between dogs? Not in the everyday sense. A healthy dog cannot catch leishmaniasis simply by playing with, sniffing or sharing a water bowl with an infected dog. The parasite needs the sandfly to complete its life cycle and move from one animal to another. There are rarer, non-sandfly routes — through blood (for example a contaminated transfusion), from a mother to her puppies during pregnancy, or through mating — but the overwhelming majority of infections in Spain come from a sandfly bite. This means you do not need to isolate an infected dog from other pets in the home; you do need to protect every dog from sandflies.

Because there is no casual dog-to-dog spread, a diagnosis in one household pet is not a reason for panic about the others — but it is a strong signal that sandflies are active in your area and that every dog you own should be properly protected.

Geography & timing

Where and when is the risk highest in Spain?

Leishmaniasis is present across large parts of mainland Spain, but the risk is not uniform. Historically the highest-prevalence areas have been the Mediterranean regions — the coastal strips and their hinterlands — along with central and southern Spain. The parasite thrives where the sandfly thrives: warm temperatures, mild winters and the right kind of humid, sheltered habitat.

Importantly, the picture is changing. Veterinary and parasitology bodies have flagged that warming temperatures are allowing sandflies to establish in areas further north where the disease was barely known a generation ago. In practical terms, that means no dog owner in Spain should assume they are completely outside the risk zone — the sensible default is to treat leishmaniasis as a nationwide concern and adjust the intensity of prevention to your local conditions with your vet’s advice.

FactorHigher riskLower risk
RegionMediterranean coast, inland valleys, central & southern Spain; increasingly the northHigh-altitude and colder inland areas (but not zero)
SeasonWarm months — broadly spring to autumn, peaking in summerCold winter months when sandflies are inactive
Time of dayDusk, night and dawnMiddle of a hot, bright day
SettingRural, garden, near vegetation, animal shelters, ruins & wallsWell-sealed indoor environment at peak biting times

Because the timing of the season varies year to year and place to place, it is worth asking your local vet directly: “How active is leishmaniasis here, and what months should I be most careful?” A vet who works in your specific area will know the local pattern far better than any general rule of thumb, and their answer should shape your prevention plan.

Moving to Spain with a pet from abroad? Our guide on moving to Spain from the UK covers the wider practicalities of relocating, and your first vet visit in Spain is the ideal moment to put a leishmaniasis prevention plan in place.
Symptoms

Symptoms of leishmaniasis in dogs

One of the most difficult things about canine leishmaniasis is that it is a master of disguise. Signs can take months — sometimes more than a year — to appear after the bite, and they develop gradually rather than suddenly. Many infected dogs stay outwardly healthy for a long time, which is exactly why regular check-ups and, where advised, screening blood tests are so valuable in endemic areas.

When signs do appear, they usually fall into two broad groups: skin (cutaneous) changes and more general (systemic) illness. A dog may show a few of these or many, and the combination varies from dog to dog.

Skin and coat changes

  • Hair loss, especially around the eyes and on the face — a classic “spectacled” appearance is often one of the earliest visible clues.
  • Dry, flaky, scaly skin (exfoliative dermatitis) — dandruff-like scaling across the body.
  • Skin sores and ulcers — particularly on the head, ear tips, nose and pressure points, and slow to heal.
  • Overgrown, brittle claws (onychogryphosis) — unusually long, curved nails are a well-recognised sign.
  • Nosebleeds (epistaxis) — sometimes the first thing an owner notices.

General and systemic signs

  • Weight loss and muscle wasting — often despite a normal or reduced appetite.
  • Lethargy and reduced exercise tolerance — a dog that tires easily or seems flat.
  • Swollen lymph nodes — enlarged glands, easily felt at the neck or behind the knees, are among the most common findings.
  • Eye problems — inflammation such as conjunctivitis or uveitis; if untreated these can threaten sight.
  • Lameness and joint pain, poor appetite, pale gums from anaemia, and increased thirst and urination as the kidneys are affected.
The most serious complication is kidney disease. Over time, leishmaniasis can cause progressive damage to the kidneys (a protein-losing kidney condition), which is the leading cause of death in affected dogs. This is why catching the disease early — before major organ damage — makes such a difference, and why any of the signs above deserve a prompt veterinary appointment rather than a “wait and see” approach.

None of these signs is unique to leishmaniasis on its own — weight loss, skin problems and lethargy have many possible causes. That is the point: in an endemic country like Spain, leishmaniasis should be on the list of possibilities your vet considers, and only a vet can tell the difference through proper examination and testing.

Diagnosis

How is leishmaniasis diagnosed?

Because the symptoms overlap with so many other conditions, leishmaniasis cannot be diagnosed by appearance alone. Your vet will combine a physical examination with laboratory testing to build a clear picture. There is no single “yes/no” test that answers every case, so vets often use more than one method.

  • Clinical examination. The vet assesses the skin, coat, claws, eyes, lymph nodes, weight and overall condition, and takes a full history — including where you live and travel.
  • Antibody (serology) tests. These look for the immune response to the parasite in the blood and can indicate how strongly the dog is reacting to infection. Quantitative antibody levels help the vet judge severity and monitor progress.
  • PCR and parasite detection. More specialised laboratory tests can detect the parasite’s DNA directly, for example from blood, lymph node or bone marrow samples — useful for confirming a diagnosis and in tricky cases.
  • Supporting blood and urine tests. General blood work and urine analysis assess the impact on the body — particularly protein levels, blood cell counts and, crucially, kidney function — which guides both treatment and prognosis.

In endemic areas, many vets recommend periodic screening of apparently healthy dogs — often as part of an annual check — precisely because early, symptom-free cases can be picked up before serious damage occurs. Whether that is right for your dog is a conversation to have with your vet, based on where you live and your dog’s lifestyle. If your dog is diagnosed, the results also give a baseline that future tests are measured against, which matters because leishmaniasis is managed over the long term rather than cured in a single course.

Treatment

Treatment and the reality of lifelong management

This is the part every owner needs to understand honestly. The good news is that leishmaniasis is treatable and many dogs, once diagnosed, go on to live good-quality, active lives for years. The harder truth is that it is very often not fully curable. Veterinary and parasitology sources are consistent on this point: no drug has been shown to reliably eliminate the parasite from the body altogether. Instead, treatment aims to control the parasite, calm the immune reaction, resolve the clinical signs and protect the organs — and that usually means ongoing care.

In practice, management of a diagnosed dog typically involves a combination of the following, always under veterinary direction:

  • Specific anti-Leishmania medication to reduce the parasite burden, often given in courses.
  • Long-term maintenance medication — frequently continued for many months or for life to keep the parasite suppressed and reduce relapses.
  • Supportive care tailored to the individual dog — for the skin, the kidneys, anaemia, a special diet and anything else the disease has affected.
  • Regular monitoring — repeat blood and urine tests to track antibody levels and, above all, kidney function, so treatment can be adjusted over time.
The honest bottom line. For most dogs, leishmaniasis becomes a lifelong condition that is managed rather than cleared away. Some dogs achieve long periods of remission with signs well controlled; others need continuous medication and can relapse, especially if treatment stops. The outlook depends heavily on how early the disease is caught and how much organ damage has already occurred — which is the single strongest argument for prevention and early testing. Every treatment decision must be made by your own vet, based on your dog’s specific test results and condition; there is no one-size-fits-all protocol.

Because management is ongoing, the costs are ongoing too. Diagnosis, initial treatment, repeat medication and the lifetime of monitoring blood tests all add up. We deliberately avoid quoting figures — they depend on your dog, your region, your vet and how the disease progresses — but it is realistic to expect that a leishmaniasis diagnosis means a recurring commitment rather than a single bill. That financial reality is exactly where pet insurance comes into the picture, and it is why when you insure matters so much.

Prevention

How to protect your dog from leishmaniasis in Spain

Since leishmaniasis is difficult to cure but largely preventable, prevention is where you should focus your energy. The strategy is simple in principle — stop the sandfly biting your dog — and the most effective approach combines several layers rather than relying on any one measure. Veterinary bodies broadly agree that the strongest protection comes from combining a proven repellent with, where appropriate, vaccination and sensible avoidance. Always agree the exact products and schedule with your vet, as recommendations and licensed products vary.

1. Sandfly repellents (the cornerstone)

The core of prevention is a veterinary product that repels and kills sandflies before they can bite. These commonly come as:

  • Insecticidal collars designed to repel sandflies, often protecting for several months at a time — popular for continuous seasonal cover.
  • Spot-on treatments applied to the skin at the back of the neck, typically repeated every few weeks through the season.

The active ingredients used against sandflies (of the pyrethroid family) are the same class veterinarians rely on for this purpose. Crucially, timing and consistency matter: protection needs to be in place before and throughout the sandfly season, and lapses leave a gap. Your vet will recommend the right product and re-application schedule for your dog and area.

2. Vaccination (where advised)

Vaccines against canine leishmaniasis are available and can be a valuable part of prevention for at-risk dogs. A vaccine does not replace repellents — the most effective protection pairs vaccination with topical insecticides — and it is not suitable for every dog. Whether to vaccinate, and when, is a decision for your vet, who will usually test the dog first to confirm it is not already infected.

3. Reduce exposure at peak biting times

  • Keep dogs indoors from dusk until after dawn during the sandfly season, when biting is most likely.
  • Use fine mesh screens on windows and doors, and consider a fine-mesh screen over outdoor kennels or sleeping areas — standard mosquito nets may be too coarse to stop such small insects, so choose a suitably fine mesh.
  • Move your dog’s bed indoors or well away from vegetation, walls, rubble and damp corners where sandflies breed and rest.
  • Keep the garden tidy — clear leaf litter and organic debris that provide breeding sites near the house.
Build a year-round habit. The best prevention is a routine you actually keep up: the right repellent maintained on schedule, vaccination if your vet advises it, and simple avoidance during peak season — reviewed at each annual check-up. Think of it the way you already think about flea, tick and worm control, not as a one-off task.
The cost — and how insurance helps

Why pet insurance matters for a condition like this

Leishmaniasis is close to the textbook example of why pet insurance exists. It is not a single emergency you pay for once; it is a long-term condition with diagnosis costs, treatment costs and — potentially for the rest of your dog’s life — the cost of repeat medication and monitoring blood tests. Faced with that kind of open-ended commitment, having cover in place can be the difference between choosing the best care for your dog and having to make decisions based purely on what you can afford that month.

Sanitas offers pet insurance in Spain through its Salud Mascotas product, and it is worth understanding how it works so you know what it can and cannot do for a condition like leishmaniasis:

  • It is reimbursement-based. You pay your vet directly and then claim the eligible costs back — so you keep your own choice of vet.
  • It reimburses 80% of eligible costs, up to €2,500 per year — subject to the policy terms, limits and exclusions. That annual allowance is designed to help exactly with the recurring bills that a chronic condition generates.
  • Free choice of veterinarian — you are not tied to a network, which matters when you have found a vet you trust to manage a long-term illness.
  • An annual preventive consultation is included — useful for the regular check-ups and, where advised, screening that help catch leishmaniasis early.
The most important thing to know: insure BEFORE diagnosis. Like virtually all pet insurance, a policy will typically exclude pre-existing conditions — anything your dog was already showing signs of, or had been diagnosed with, before the cover started. If your dog is diagnosed with leishmaniasis first and you take out a policy afterwards, the leishmaniasis and its ongoing treatment are very unlikely to be covered. The time to arrange cover is while your dog is healthy — ideally as soon as you have a dog in Spain — not after a problem appears. Acceptance and the exact terms depend on the insurer’s rules.

If you are weighing up cover, our dedicated guides walk through the options: pet insurance in Spain for the overview, and dog insurance if you specifically own a dog. Cat owners can read about cat insurance too — while leishmaniasis is overwhelmingly a disease of dogs, cats living in Spain benefit from cover for the many other conditions they can face. If you would rather just talk it through, an English-speaking adviser can help you get a quote or answer questions via our contact page.

Stay aware

Other seasonal dangers for pets in Spain

Leishmaniasis is the most significant long-term parasitic threat, but it is not the only seasonal hazard for pets in Spain. Building good habits around one risk makes it easier to stay on top of the others, and the same annual vet visit is a natural moment to review them all.

The pine processionary caterpillar is a sudden, acute emergency in late winter and spring — the opposite of leishmaniasis in timing and speed, but just as important to know about. And in the fierce Spanish summer, heatstroke is a genuine and rapid killer, especially for dogs walked in the heat of the day. Notice how the timings interlock: the same warm months that bring peak sandfly activity are also the peak heatstroke season, so summer is when your guard should be highest on several fronts at once.

Protect your dog — get a pet insurance quote

A lifelong condition like leishmaniasis is exactly what cover is for — but only if it is in place before diagnosis. Tell us about your pet and an English-speaking adviser will find a Sanitas plan that reimburses your vet bills.

Get My Quote →
FAQ

Leishmaniasis in dogs: frequently asked questions

In most cases, no — not in the sense of completely eliminating the parasite from the body. Veterinary sources agree that no drug reliably achieves a full cure. However, leishmaniasis is very treatable: with veterinary management, many dogs achieve good control of their symptoms and long periods of remission, and can live active, good-quality lives for years. It is best thought of as a lifelong condition that is managed — much like some chronic illnesses in people — rather than a disease that is cured in a single course. The earlier it is caught, the better the outlook, because less organ damage has occurred. Your vet will guide treatment based on your dog’s test results.
+
Early signs are often subtle and easy to miss. Some of the first things owners notice are hair loss around the eyes and on the face, dry flaky skin or dandruff, slow-healing sores (especially on the head and ear tips), overgrown claws, occasional nosebleeds, gradual weight loss, tiredness, and swollen glands (lymph nodes). Because these signs develop slowly and overlap with many other conditions, any of them warrants a vet visit rather than a wait-and-see approach — early diagnosis makes a real difference to the outcome.
+
Prevention focuses on stopping the sandfly biting, and the strongest protection combines several layers: a veterinary sandfly repellent (an insecticidal collar or a spot-on treatment) kept up consistently through the season; vaccination where your vet advises it; keeping your dog indoors from dusk until after dawn during the warm months; using fine mesh screens on windows, doors and sleeping areas; and keeping the garden clear of the leaf litter and damp debris where sandflies breed. Ask your vet to recommend the right products and schedule for your area, and treat it as a year-round routine like flea and tick control.
+
Not through normal contact. A dog cannot pass leishmaniasis to another dog or to a person simply by being near them, playing or sharing bowls — the parasite needs the sandfly to spread from one animal to another. There are rarer non-sandfly routes (such as through blood, from mother to puppies, or through mating), but these are uncommon. It is a zoonotic disease, meaning people can be infected, but they catch it the same way dogs do — from a sandfly bite — not from the dog itself. So you do not need to isolate an infected pet, but you should make sure every dog in the household is properly protected from sandflies.
+
Sandflies are most active in the warm months — broadly from spring through to autumn, with the greatest activity in summer — and within each day they bite mainly at dusk, through the night and around dawn. Cold winter months are low risk because sandflies become inactive. The exact timing varies by region and year, and warming temperatures are extending activity into areas and periods where it was once rare, so it is worth asking your local vet how long the season lasts where you live and planning your dog’s protection to cover the whole of it.
+
It can — but only if the policy was already in place before your dog showed signs of or was diagnosed with the disease. Pet insurance, including Sanitas Salud Mascotas, typically excludes pre-existing conditions, so if you insure after a diagnosis the leishmaniasis is very unlikely to be covered. Where cover is in place beforehand, Sanitas Salud Mascotas reimburses 80% of eligible costs up to €2,500 per year, subject to the policy terms, limits and exclusions — which is designed to help with exactly the kind of ongoing treatment and monitoring costs this condition creates. Because it is a lifelong condition, insuring while your dog is healthy is the key. Acceptance and exact terms depend on the insurer’s rules.
Sources

Sources & further reading

This guide is general information for dog owners, not veterinary advice. Always consult your own vet about diagnosis, treatment and prevention for your dog. Key veterinary and parasitology sources include:

• ESCCAP — Guideline GL5: Control of Vector-Borne Diseases in Dogs and Cats: esccap.org/guidelines/gl5

• Companion Animal Parasite Council (CAPC) — Leishmaniasis: capcvet.org/guidelines/leishmaniasis

• LeishVet guidelines for the practical management of canine leishmaniosis: ncbi.nlm.nih.gov/pmc/articles/PMC3125381

• Canine Leishmaniasis: Update on Epidemiology, Diagnosis, Treatment, and Prevention (peer-reviewed review): ncbi.nlm.nih.gov/pmc/articles/PMC9416075